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4-Chlorophenoxyacetic acid(4-CPA)

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Introduction
4-Chlorophenoxyacetic acid Basic information
Product Name: 4-Chlorophenoxyacetic acid
Synonyms: 4-CHLOROPHENOXYACETIC ACID PESTANAL,250;P-CHLOROPHENOXY ACETIC ACID, 1GM, NEAT;P-CHLOROPHENOXYACETIC ACID PLANT CELLCUL TURE TESTE;4-ChlorophenoxyaceticAcid(4-Cpa);4-cpa(bsi,e-iso);MONOCHLOROPHENOXYACETICACID;4-CHLOROPHENOXYACETATE;BRAKENTROLE
CAS: 122-88-3
MF: C8H7ClO3
MW: 186.59
EINECS: 204-581-3
Product Categories: Pharmaceutical Raw Materials;Phenoxyacetic Acids and Alcohols (substituted);Organic acids;PLANT GROWTH REGULATOR;Auxins;Biochemistry;Plant Growth Regulators
Mol File: 122-88-3.mol
4-Chlorophenoxyacetic acid Structure
4-Chlorophenoxyacetic acid Chemical Properties
Melting point  157-159 °C
Boiling point  266.91°C (rough estimate)
density  1.3245 (rough estimate)
refractive index  1.5250 (estimate)
storage temp.  0-6°C
solubility  957mg/l
form  crystalline
pka pK1: 3.10 (25°C)
color  White to light beige
Water Solubility  848mg/L(25 ºC)
BRN  1211804
CAS DataBase Reference 122-88-3(CAS DataBase Reference)
NIST Chemistry Reference 4-Chlorophenoxyacetic acid(122-88-3)
EPA Substance Registry System 4-Chlorophenoxyacetic acid (122-88-3)
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-R22
Safety Statements  22-24/25
RIDADR  2811
WGK Germany  1
RTECS  AG0175000
21
TSCA  Yes
HazardClass  IRRITANT
HS Code  29189090
Hazardous Substances Data 122-88-3(Hazardous Substances Data)
Toxicity LD50 oral in rat: 850mg/kg
MSDS Information
Provider Language
4-CPA English
SigmaAldrich English
ACROS English
ALFA English
4-Chlorophenoxyacetic acid Usage And Synthesis
Chemical Properties white to light beige powder
Uses 2-(4-Chlorophenoxy)acetic Acid is used in the synthesis of a new class of hypoxia-inducible factor-1 inhibitors.
Definition ChEBI: A chlorophenoxyacetic acid that is phenoxyacetic acid carrying a chloro substituent at position 4.
Hazard Moderately toxic; mutagen.
Safety Profile Moderately toxic by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl-.
Purification Methods Crystallise the acid from EtOH. It is a plant growth substance and a herbicide. [Beilstein 6 IV 845.]
4-Chlorophenoxyacetic acid Preparation Products And Raw materials
Raw materials Iodine-->Chloroacetic acid-->4-Chlorophenol-->Phenoxyacetic acid
Preparation Products 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate-->Sodium 4-chlorophenoxyacetate
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